Peroni D G, Piacentini G L, Zizzo M G, Boner A l
Clinica Pediatrica Università di Verona, Italy.
Monaldi Arch Chest Dis. 1998 Apr;53(2):134-7.
In the present study we have assessed the prevalence of asthma-related symptoms in school children resident in the urban area of Verona, in the north east of Italy, as part of the International Study of Asthma and Allergies in Childhood (ISAAC). The entirely of the population of children aged 6-7 yrs (total 2,350, from 64 schools) and 13-14 years (total 2,500 from 42 schools) living in the area was selected. A questionnaire was distributed at school. This was addressed to the parents of the younger population and distributed directly to the older children. In the two groups 2,091 (89%) and 2,179 (87%) questionnaires were returned, respectively. The results obtained show a more frequent history of "wheeling ever" in the young population compared to the older group (23.2 versus 7.9%, respectively) (p < 0.001). There was no difference in the prevalence of wheezing in the last 12 months (7.3 and 7.4%, respectively), and of asthma (4.6 and 3.5%, respectively). In the older group there was a higher incidence of exercise-induced wheezing (12.0 versus 3.2%), which was particularly significant in the females compared to males (14.2 versus 10.0, respectively; p < 0.01). Our data confirm that there is a marked variation in the prevalence of asthma and asthma-related respiratory symptoms in different centres throughout the world, since we obtained a lower percentage of reported symptoms in comparison to other ISAAC centres.
在本研究中，作为“儿童哮喘和过敏国际研究”（ISAAC）的一部分，我们评估了居住在意大利东北部维罗纳市区的学童中与哮喘相关症状的患病率。选取了该地区所有6至7岁（共2350名，来自64所学校）和13至14岁（共2500名，来自42所学校）的儿童。在学校发放了问卷。问卷发给较年幼儿童的家长，并直接分发给较大的儿童。两组分别回收了2091份（89%）和2179份（87%）问卷。结果显示，较年幼组“曾经喘息”的病史比年长组更常见（分别为23.2%和7.9%）（p<0.001）。过去12个月内喘息的患病率（分别为7.3%和7.4%）以及哮喘的患病率（分别为4.6%和3.5%）没有差异。在年长组中，运动诱发喘息的发生率较高（12.0%对3.2%），女性尤为显著，与男性相比分别为14.2%和10.0%（p<0.01）。我们的数据证实，世界各地不同中心哮喘及与哮喘相关的呼吸道症状患病率存在显著差异，因为与其他ISAAC中心相比，我们获得的报告症状百分比更低。
