Ohla Victoria, Ciarlini Pedro D S C, Goldsmith Jeffrey D, Kasper Ekkehard M
Division of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Surg Neurol Int. 2013 Jun 19;4:82. doi: 10.4103/2152-7806.113648. Print 2013.
Cellular myxoma is a histopathologically distinctive benign neoplasm, which has often been categorized among the broad category of benign mesenchymal tumors with myxoid stroma and fibroblast- and/or myofibroblast-like cells. These tumors can arise in any of the large muscles and are usually found in the thigh, shoulder, buttocks, and upper arm, and more rarely in the head and neck or in small muscles of the hand.
Here we illustrate the case of a 57-year-old female with a spinal lesion, who initially presented with complaints of vague pelvic discomfort but no focal neurological deficits. Imaging revealed a sharply demarcated paraspinal lesion concerning for a tumorous growth. The lesion was excised in toto and a detailed immuno-histopathological analysis was performed revealing the diagnosis of a cellular myxoma. Postoperative imaging showed a gross total resection and the patient is under clinical surveillance since, with no signs of recurrence after 42 months.
Although very rare, this entity should be considered in the differential diagnosis of any spinal and paraspinal mass to allow for adequate treatment, which requires wide excision with clean margins to avoid any local recurrence.
细胞性黏液瘤是一种组织病理学上独特的良性肿瘤，常被归类于具有黏液样基质和成纤维细胞及/或肌成纤维细胞样细胞的广泛良性间叶性肿瘤类别中。这些肿瘤可发生于任何大肌肉，通常见于大腿、肩部、臀部和上臂，在头颈部或手部小肌肉中则较为罕见。
在此，我们展示一例57岁女性脊柱病变病例，该患者最初表现为盆腔模糊不适，但无局灶性神经功能缺损。影像学检查发现一个边界清晰的椎旁病变，怀疑为肿瘤性生长。病变被完整切除，并进行了详细的免疫组织病理学分析，确诊为细胞性黏液瘤。术后影像学检查显示肿瘤全切，自那以后患者一直处于临床监测中，42个月后无复发迹象。
尽管这种实体非常罕见，但在任何脊柱和椎旁肿块的鉴别诊断中都应考虑到，以便进行充分治疗，这需要进行切缘干净的广泛切除以避免局部复发。
