Degtiarev A N, Mikhaĭlovskaia A Iu, Vasilevskaia L S, Sergienko V I
Institute of Physico-Chemical Medicine, Ministry of Public Health of the Russian Federation, Moscow, Russia.
Eksp Klin Farmakol. 1998 May-Jun;61(3):35-7.
The effect of cholisorb and its salt (Na and K) forms on the external secretion of the liver was studied. The cholagogic effect of the H-form of cholisorb and its salt forms was demonstrated in dog experiments. The effect of the H-form proved to be stronger. This effect was associated with decreased absorption of bile acids and cholesterol in the intestine and disturbed hepato-intestinal biliary cycle as a result of which adaptation mechanisms directed at restoration of this cycle are apparently switched on.
研究了胆吸附剂及其盐（钠和钾）形式对肝脏外分泌的影响。在犬实验中证实了胆吸附剂H型及其盐形式的利胆作用。结果表明H型的作用更强。这种作用与肠道中胆汁酸和胆固醇的吸收减少以及肝肠胆汁循环紊乱有关，结果显然启动了旨在恢复该循环的适应机制。
