Martinez G, Carnazza M L, Campisi A, Sorrenti V, Di Giacomo C, Perez-Polo J R, Vanella A
Institute of Biological Chemistry, Faculty of Pharmacy, University of Catania, Italy.
Neurochem Res. 1998 Jul;23(7):961-8. doi: 10.1023/a:1021080321320.
The present paper reports the effects of GSH depletion (diethylmaleate induced) on partial cerebral ischemia and reperfusion for 7 and 20 days. Our results confirm that there is a paradoxical protective effect of the GSH-depletor and suggest an improved neuronal trophism induced by diethylmaleate treatment.