Myers C, Duncan K R, Gowland P A, Johnson I R, Baker P N
Department of Obstetrics, Midwifery and Gynaecology, City Hospital, Nottingham, UK.
Br J Radiol. 1998 May;71(845):549-51. doi: 10.1259/bjr.71.845.9691901.
Echo planar imaging is a form of MRI with short image acquisition times, which permits in utero fetal imaging without motion artefacts. Echo planar imaging has been used to measure accurately fetal organ volume and to assess placental function. Two small animal studies have suggested the possibility of intrauterine growth restriction consequent upon MRI. We thus performed a prospective study of pregnancies in which fetuses were exposed to echo planar imaging, compared with a control group in which there was no in utero echo planar imaging exposure. There were no significant differences between the groups when maternal age, parity, proportion of smokers and proportion of Caucasian women were compared. Although the gestational age of delivery was lower in the echo planar imaging group, the proportion of women delivering prematurely was not significantly different. Although infant birthweights were significantly lower in the MRI group, the corrected birthweight for gestational age centiles (individualized birthweight ratio) was not significantly different between the two groups. In utero exposure to echo planar imaging thus did not have a marked effect on intrauterine fetal growth. A 10 year follow-up study of all infants imaged in utero is being performed.
回波平面成像是一种具有短图像采集时间的磁共振成像形式，它允许进行无运动伪影的子宫内胎儿成像。回波平面成像已被用于精确测量胎儿器官体积和评估胎盘功能。两项小动物研究表明了磁共振成像导致子宫内生长受限的可能性。因此，我们对胎儿接受回波平面成像的妊娠进行了一项前瞻性研究，并与未进行子宫内回波平面成像暴露的对照组进行了比较。在比较产妇年龄、产次、吸烟者比例和白人女性比例时，两组之间没有显著差异。虽然回波平面成像组的分娩孕周较低，但早产女性的比例没有显著差异。虽然磁共振成像组的婴儿出生体重显著较低，但两组之间根据孕周百分位数校正的出生体重（个体化出生体重比）没有显著差异。因此，子宫内暴露于回波平面成像对子宫内胎儿生长没有显著影响。正在对所有在子宫内成像的婴儿进行为期10年的随访研究。
