Comellini L, Tozzola A, Baldi F, Brusa S, Serra L, Agostoni C, Scaglia M
Division of Paediatrics, Imola Hospital, Italy.
Ann Trop Paediatr. 1998 Mar;18(1):41-3. doi: 10.1080/02724936.1998.11747924.
We report a case of congenital malaria in a newborn whose mother is a native of Zaire now living in Italy. The baby developed remittent fever in the 3rd week of life with anaemia and hepatosplenomegaly. Malaria parasites found in blood smears and erroneously diagnosed initially as Plasmodium falciparum were subsequently recognized as Plasmodium vivax. On the basis of the first diagnosis, treatment with quinine chlorhydrate was successfully undertaken without significant side-effects. P. vivax parasites were also recovered a posteriori in blood smears of the mother who was febrile during the week of her delivery. This report suggests that symptomatic congenital malaria may be more common than is generally thought and should be suspected in non-malarious countries in febrile newborns born to mothers who have travelled in or immigrated from malaria-endemic areas.
我们报告了一例新生儿先天性疟疾病例,其母亲是扎伊尔本地人,现居住在意大利。婴儿在出生后第3周出现弛张热,并伴有贫血和肝脾肿大。在血涂片上发现了疟原虫,最初被误诊为恶性疟原虫,后来被确认为间日疟原虫。基于最初的诊断,成功地使用了水合氯喹进行治疗,且无明显副作用。在分娩当周发热的母亲的血涂片中也事后发现了间日疟原虫。本报告提示,有症状的先天性疟疾可能比普遍认为的更为常见,在非疟疾国家,对于出生于曾前往疟疾流行地区旅行或从疟疾流行地区移民而来的发热母亲所生的新生儿,应怀疑患有先天性疟疾。