Siqueira J F, Batista M M, Fraga R C, de Uzeda M
Estácio de Sá University, Rio de Janeiro, Brazil.
J Endod. 1998 Jun;24(6):414-6. doi: 10.1016/S0099-2399(98)80023-X.
The antibacterial effect of endodontic irrigants was evaluated against four black-pigmented Gram-negative anaerobes and four facultative anaerobic bacteria by means of the agar diffusion test. All solutions used were inhibitory against all bacterial strains tested. A 4% NaOCl solution provided the largest average zone of bacterial inhibition of this study that was significantly superior when compared with the other solutions, except 2.5% NaOCl (p < 0.05). Based on the averages of the diameters of the zones of bacterial growth inhibition, the antibacterial effects of the solutions could be ranked from strongest to weakest as follows: 4% NaOCl; 2.5% NaOCl; 2% chlorhexidine; 0.2% chlorhexidine, EDTA, and citric acid; and 0.5% NaOCl.
通过琼脂扩散试验评估了根管冲洗剂对四种产黑色素革兰氏阴性厌氧菌和四种兼性厌氧菌的抗菌效果。所有使用的溶液对所有测试菌株均有抑制作用。4%次氯酸钠溶液在本研究中提供了最大的平均细菌抑制圈，与其他溶液相比，除2.5%次氯酸钠外，均具有显著优势（p<0.05）。根据细菌生长抑制圈直径的平均值，溶液的抗菌效果从强到弱依次为：4%次氯酸钠；2.5%次氯酸钠；2%氯己定；0.2%氯己定、乙二胺四乙酸和柠檬酸；以及0.5%次氯酸钠。
