Vazquez M D, Bouchet P, Foliguet B, Gérard H, Mallet J L, Leheup B
Département de Cytologie, Histologie et Embryologie, Faculté de Médecine, Vandoeuvre-lès-Nancy, France.
Int J Dev Biol. 1998 May;42(4):621-4.
In the mouse, Sryis expressed by somatic cells in the genital ridge and leads to initiate the transformation of the indifferent gonad into a testis. Here, we have examined the segmented female and male mesonephroi over the developmental period when the initiation of seminiferous cord formation takes place. We have generated three-dimensional models which reveal structural differences between male and female mesonephric tubules at 11.5, 13.5 and 14.5 days post coitum. We evaluate, following structural parameters, that form and orientation of the tubules could evolve differently in both sexes. We propose that the structural organization of the mesonephric tubules presents an early dimorphism.
在小鼠中，Sry由生殖嵴中的体细胞表达，并导致原始性腺向睾丸转变。在此，我们研究了在生精索形成起始的发育阶段的分段雌性和雄性中肾。我们生成了三维模型，揭示了交配后11.5、13.5和14.5天雄性和雌性中肾小管之间的结构差异。我们根据结构参数评估，肾小管的形态和方向在两性中可能有不同的演变。我们提出，中肾小管的结构组织呈现早期二态性。
