Hettiarachchi K, Ha Y, Tran T, Cheung A P
Life Sciences Division, SRI International, Menlo Park, CA 94025, USA.
J Pharm Biomed Anal. 1995 Apr;13(4-5):515-23. doi: 10.1016/0731-7085(95)01261-i.
Polyoxometalates (POM) are polymers of transition metal oxides. They are widely used as analytical reagents and reaction catalysts. Some have anti-viral properties and are being investigated as anti-HIV agents. Due to solubility and stability limitations, separation methods for POM are rare in the literatures. This paper presents a HPLC and a CZE method for the analysis of sodium tungstate, its equilibrium products and isopolyanions. The methods are simple and sensitive, and can be used to monitor the purity, stability and solution equilibria of POM.
多金属氧酸盐（POM）是过渡金属氧化物的聚合物。它们被广泛用作分析试剂和反应催化剂。一些具有抗病毒特性，正在作为抗HIV药物进行研究。由于溶解性和稳定性的限制，文献中很少有多金属氧酸盐的分离方法。本文介绍了一种用于分析钨酸钠、其平衡产物和同多阴离子的高效液相色谱法和毛细管区带电泳法。这些方法简单且灵敏，可用于监测多金属氧酸盐的纯度、稳定性和溶液平衡。
