Rosenson R S, Tangney C C
Preventive Cardiology Center, Rush Presbyterian St. Luke's Medical Center, Chicago, IL 60612, USA.
Clin Hemorheol Microcirc. 1998 Jul;18(2-3):191-4.
Reliable plasma viscosity measurements are required for cardiovascular risk factor assessment. This study was designed to examine the influence of tourniquet pressure and duration on plasma viscosity measurement with a coaxial cylinder at 37 degrees C. Plasma viscosity was evaluated at low (40 mm Hg) and high (mean arterial blood pressure plus 10 mm Hg) tourniquet pressure and at two time intervals following (0-1 and 4-5 min) of tourniquet application in 38 healthy adults. Longer duration of tourniquet application was accompanied by a significant increase in plasma viscosity at both low (1.356 +/- 0.067 mPa s versus 1.393 +/- 0.067 mPa s (p = 0.0001)) and high (1.321 +/- 0.071 mPa s versus 1.430 +/- 0.086 mPa s (p = 0.0002)) tourniquet pressures. Plasma viscosity values were not influenced by the magnitude of tourniquet pressure. The accuracy of plasma viscosity measurements can be improved by sample acquisition within 1 min following tourniquet application.
心血管危险因素评估需要可靠的血浆粘度测量。本研究旨在考察止血带压力和持续时间对在37℃下使用同轴圆柱体测量血浆粘度的影响。在38名健康成年人中，分别在低（40毫米汞柱）和高（平均动脉血压加10毫米汞柱）止血带压力下，以及在止血带应用后的两个时间间隔（0 - 1分钟和4 - 5分钟）评估血浆粘度。止血带应用时间延长伴随着低（1.356±0.067毫帕·秒对1.393±0.067毫帕·秒（p = 0.0001））和高（1.321±0.071毫帕·秒对1.430±0.086毫帕·秒（p = 0.0002））止血带压力下血浆粘度的显著增加。血浆粘度值不受止血带压力大小的影响。在止血带应用后1分钟内采集样本可提高血浆粘度测量的准确性。
