Hagenouw R R, Bridenbaugh P O, van Egmond J, Stuebing R
Anesth Analg. 1986 Nov;65(11):1175-80.
The effect of inflation pressure (300 and 400 mm Hg) and method of exsanguination (gravity and Esmarch bandage) on the time of onset and the severity of tourniquet-induced pain in the lower extremity was investigated in 11 unmedicated adult volunteers. Each volunteer underwent eight experiments in a random order. A visual analog scale was used to assess pain and discomfort. Blood pressure and pulse rate were measured continuously. Experiments were concluded when the pain rose to a prefixed level. All experiments were performed using a standard orthopedic tourniquet (7 cm wide). Ten additional experiments were carried out using a Bier blockade tourniquet (5 cm wide). There were no differences in duration of tourniquet inflation between inflation pressures nor between methods of exsanguination. There was a small and transient but nevertheless statistically significant increase in blood pressure caused by inflation and a significantly larger increase just before deflation. The 5-cm tourniquet experiments, otherwise identical to the 7-cm tourniquet experiments, were tolerated significantly longer due to a longer time of onset and less severe pain. The 5-cm tourniquet also needed significantly higher inflation pressures to fully occlude the arterial supply (240-450 mm Hg). In all instances, 260 mm Hg was adequate to fully occlude the arterial supply when a 7-cm tourniquet was used. Only half of the experiments were concluded due to intolerable pain at the site of the tourniquet. Most of the others were concluded due to pain mainly in the calf or pain throughout the leg.(ABSTRACT TRUNCATED AT 250 WORDS)
在11名未用药的成年志愿者中,研究了充气压力(300和400毫米汞柱)和放血方法(重力放血和埃斯马赫绷带)对下肢止血带所致疼痛的发作时间和严重程度的影响。每位志愿者按随机顺序进行8次实验。使用视觉模拟量表评估疼痛和不适。持续测量血压和脉搏率。当疼痛升至预定水平时结束实验。所有实验均使用标准的骨科止血带(7厘米宽)进行。另外使用比尔阻断止血带(5厘米宽)进行了10次实验。充气压力之间以及放血方法之间的止血带充气持续时间没有差异。充气会导致血压有小幅短暂但具有统计学意义的升高,放气前升高幅度明显更大。5厘米宽的止血带实验在其他方面与7厘米宽的止血带实验相同,但由于发作时间更长且疼痛较轻,所以耐受时间明显更长。5厘米宽的止血带也需要明显更高的充气压力才能完全阻断动脉供血(240 - 450毫米汞柱)。在所有情况下,使用7厘米宽的止血带时,260毫米汞柱足以完全阻断动脉供血。只有一半的实验因止血带部位难以忍受的疼痛而结束。其他大多数实验结束是由于主要在小腿的疼痛或整条腿的疼痛。(摘要截短至250字)