Eberhart L H, Döring H J, Holzrichter P, Roscher R, Seeling W
Department of Anaesthesiology, University of Ulm, Germany.
Eur J Anaesthesiol. 1998 Jul;15(4):446-52. doi: 10.1046/j.1365-2346.1998.00321.x.
A double-blind randomized study was performed in 100 patients undergoing thyroidectomy to evaluate the effect of positive therapeutic suggestions made during neurolept-anaesthesia. The classic droperidol-fentanyl-N2O technique was used as these drugs preserve the neurophysiological functions required to process the information in the therapeutic suggestions given during general anaesthesia. Patients in the suggestion group heard positive non-affirmative suggestions during the whole operation. An autoreverse tape player was used. The control group listened to an empty tape. Both groups were comparable with respect to demographic variables, anaesthetic technique, drug dosage, duration of anaesthesia and surgery. Patients in the suggestion group suffered significantly less from post-operative nausea or vomiting (suggestion: 47.2% vs. control: 85.7%) and required less anti-emetic treatment (suggestion: 30.6% vs. control: 68.6%). We conclude that therapeutic suggestions heard during neurolept-anaesthesia are processed and decrease post-operative nausea and vomiting in patients after thyroidectomy.
对100例接受甲状腺切除术的患者进行了一项双盲随机研究，以评估在神经安定麻醉期间给予积极治疗性暗示的效果。采用经典的氟哌利多-芬太尼-N₂O技术，因为这些药物能保留在全身麻醉期间处理治疗性暗示中信息所需的神经生理功能。暗示组的患者在整个手术过程中听到积极的非肯定性暗示。使用了自动反转磁带播放机。对照组听空白磁带。两组在人口统计学变量、麻醉技术、药物剂量、麻醉和手术持续时间方面具有可比性。暗示组患者术后恶心或呕吐的发生率显著较低（暗示组：47.2% 对比对照组：85.7%），且所需的止吐治疗较少（暗示组：30.6% 对比对照组：68.6%）。我们得出结论，在神经安定麻醉期间听到的治疗性暗示会被处理，并减少甲状腺切除术后患者的术后恶心和呕吐。
