Gosden P E, MacGowan A P, Bannister G C
Department of Medical Microbiology, Southmead Health Services NHS Trust, Westbury-on-Trym, Bristol, UK.
J Hosp Infect. 1998 Jul;39(3):173-80. doi: 10.1016/s0195-6701(98)90255-9.
Small numbers of organisms can cause orthopaedic implant infections, which give rise to a considerable degree of morbidity and also mortality. The periprosthetic infection rates have been shown to correlate with the number of airborne bacteria within 30 cm of the wound. This is influenced by factors such as the number of operating theatre personnel, their clothing and the type of ventilation system used. Guidance on routine bacteriological monitoring of ultraclean air theatres, based on the Department of Health document Health Technical Memorandum 2025, is discussed. Factors important in minimizing the number of postoperative implant infections such as the use of ultraclean air, ultraviolet radiation, different types of surgical clothing, prophylactic antibiotics and host-related factors are also discussed. The importance of proper scientific investigation into the effectiveness of practical preventative measures in the operating room is emphasized.
少量微生物即可导致骨科植入物感染，这会引发相当程度的发病率甚至死亡率。已表明假体周围感染率与伤口30厘米范围内空气中细菌数量相关。这受到诸如手术室人员数量、其着装以及所使用通风系统类型等因素的影响。本文讨论了基于卫生部文件《健康技术备忘录2025》对超净手术室进行常规细菌学监测的指导意见。还讨论了在尽量减少术后植入物感染数量方面重要的因素，如使用超净空气、紫外线辐射、不同类型的手术服装、预防性抗生素以及宿主相关因素。强调了对手术室实际预防措施有效性进行恰当科学调查的重要性。
