Brazitikos P D, D'Amico D J, Bochow T W, Hmelar M, Marcellino G R, Stangos N T
Department of Ophthalmology, Democritus University of Thrace, Alexandroupolis, Greece.
Invest Ophthalmol Vis Sci. 1998 Aug;39(9):1667-75.
To evaluate the performance in ocular surgery and the ocular tissue interactions resulting from increasing the maximum repetition rate of a pulsed-mode erbium:YAG laser system from 30 to 200 pulses per second.
An erbium:YAG laser was used that emitted at 2.94 microm with an output graduated from 0.2 mJ to 25 mJ and a repetition rate from 2 Hz to 200 Hz and that was equipped with a flexible optical fiber attached to various interchangeable 20-gauge endoprobes to perform ocular surgery in enucleated pig eyes. The specific maneuvers were performed in close contact in nontransmitting aqueous media and included inner retinal ablation, retinotomy, lens capsulotomy, lens ablation, iridotomy, and iridectomy. Selected tissue specimens were examined by light microscopy.
Increasing the repetition rate to the 200-Hz range significantly improved the smoothness, continuity, and speed of all surgical maneuvers. Compared with the 30-Hz rate, substantially lower energies per pulse were efficient with the 200-Hz rate. The "sticking effect" between the tip of the probe and the target tissue at low-repetition rates, which resulted in discontinuation of the surgical maneuver, particularly during lens surgery, was eliminated with the use of high-repetition rates. Use of high-repetition rates produced a zone of residual thermal damage less than 30 microm in all ocular tissues. The histologic findings of tissue interactions were comparable to those obtained in published studies in which the same wavelength and low hertz rates were used.
The high-repetition-rate erbium:YAG laser technology described is advantageous, compared with low-repetition-rate erbium:YAG lasers, and is applicable in a variety of ocular surgical procedures. Innovations in endoprobe design and further study will determine its role in contemporary ocular surgery.
评估将脉冲模式铒:钇铝石榴石激光系统的最大重复频率从每秒30次提高到200次时在眼科手术中的性能以及眼部组织的相互作用。
使用的铒:钇铝石榴石激光发射波长为2.94微米,输出能量从0.2毫焦到25毫焦,重复频率从2赫兹到200赫兹,配备有一根柔性光纤,连接到各种可互换的20号眼内探头,用于在摘除的猪眼中进行眼科手术。具体操作在非透光性房水介质中紧密接触进行,包括视网膜内层消融、视网膜切开术、晶状体囊切开术、晶状体消融、虹膜切开术和虹膜切除术。选取的组织标本进行光学显微镜检查。
将重复频率提高到200赫兹范围显著改善了所有手术操作的平滑度、连续性和速度。与30赫兹的频率相比,200赫兹频率下每个脉冲所需的能量大幅降低。低重复频率下探头尖端与目标组织之间的“粘连效应”,这会导致手术操作中断,尤其是在晶状体手术期间,通过使用高重复频率得以消除。使用高重复频率在所有眼部组织中产生的残余热损伤区域小于30微米。组织相互作用的组织学结果与使用相同波长和低赫兹频率的已发表研究结果相当。
与低重复频率的铒:钇铝石榴石激光相比,所描述的高重复频率铒:钇铝石榴石激光技术具有优势,适用于多种眼科手术。眼内探头设计的创新和进一步研究将确定其在当代眼科手术中的作用。