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[关于捷克斯洛伐克1960 - 1973年间子宫内膜癌和卵巢癌发病率上升的研究]

[Studies on the increase in the incidence of endometrial and ovarian in cancer in Czechoslovakia during 1960-1973].

作者信息

Rosol M, Strnad L, Havel V, Andrýs J, Vácha K

出版信息

Zentralbl Gynakol. 1976;98(3):175-82.

PMID:970016
Abstract

During the time period of the last 12 years the incidence of the endometrium carcinoma in the whole CSSR rised to 155,5% in the consideration of the incidence in the years 1961 to 1963. In the same time period the incidence of the ovarial carcinoma has grown up to 117,8% only, what seems to be still in the limits of average incidence shift of all female malignancies in the CSSR (117,1%). The rising incidence of endometrium carcinoma affects primarily the elderly women, but testiefies also that this malignancy is among them today much more frequent. Therefore the rising incidence cannot be explained only as a manifestation of elderly of the female population. In agreement with this reality the endometrium carcinoma is today diagnosed significantly more frequently also among the younger women (at least since 40 years of age). The totals of all endometrium carcinomas rised even more than incidence. The gynaecologists meet today 162% of such malignancies in comparison with the numbers in the years 1961-1963. It means that in the whole CSSR yearly 500 endometrium carcinomas more are diagnosed than before 12 years. The incidence of cervix carcinoma dropped during the same period significantly and the endometrium carcinoma became therefore nearly as frequent as cervical malignancy (1:1,2). Possible reasons of these frequency changes are discussed.

摘要

在过去12年期间,与1961年至1963年的发病率相比,捷克斯洛伐克社会主义共和国(CSSR)子宫内膜癌的发病率升至155.5%。在同一时期,卵巢癌的发病率仅增长到117.8%,这似乎仍在捷克斯洛伐克社会主义共和国所有女性恶性肿瘤平均发病率变化的范围内(117.1%)。子宫内膜癌发病率的上升主要影响老年女性,但也证明这种恶性肿瘤在她们当中如今更为常见。因此,发病率的上升不能仅解释为女性人口老龄化的表现。与此现实相符的是,如今在年轻女性(至少40岁及以上)中,子宫内膜癌的诊断也明显更为频繁。所有子宫内膜癌的总数增长甚至超过了发病率。与1961 - 1963年的数字相比,如今妇科医生遇到的此类恶性肿瘤病例增加了162%。这意味着在整个捷克斯洛伐克社会主义共和国,每年诊断出的子宫内膜癌比12年前多500例。同期宫颈癌的发病率显著下降,因此子宫内膜癌几乎变得与宫颈癌一样常见(1:1.2)。文中讨论了这些发病率变化的可能原因。

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Oestrogen and endometrial cancer: a reappraisal.雌激素与子宫内膜癌:重新评估
J R Soc Med. 1981 Jun;74(6):403-6. doi: 10.1177/014107688107400601.

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