Heyland D K
Department of Medicine, Queen's University Faculty of Health Sciences, Kingston, Ontario, Canada.
Crit Care Clin. 1998 Jul;14(3):423-40. doi: 10.1016/s0749-0704(05)70009-9.
Providing nutritional support has become a standard component of managing critically ill patients. While many studies have documented that providing nutritional support can change nutritional outcomes (e.g., amino acid profile, weight gain, nitrogen balance), data are lacking that demonstrate that nutrition actually influences clinically importance endpoints. This article systematically reviews and critically appraises the literature, examining the relationship between nutritional support and infectious morbidity and mortality in the critically ill patient. In addition, evidence-based recommendations are made.
提供营养支持已成为危重症患者管理的标准组成部分。虽然许多研究记录了提供营养支持可改变营养结局（如氨基酸谱、体重增加、氮平衡），但缺乏数据表明营养实际上会影响临床重要终点。本文系统回顾并批判性评价了相关文献，探讨了危重症患者营养支持与感染性发病率和死亡率之间的关系。此外，还提出了基于证据的建议。
