Wolk A, Vessby B, Ljung H, Barrefors P
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden.
Am J Clin Nutr. 1998 Aug;68(2):291-5. doi: 10.1093/ajcn/68.2.291.
We evaluated whether the adipose tissue content of 2 fatty acids of exogenous origin specific for ruminant fat, 15:0 and 17:0, reflect average long-term dairy fat consumption in free-living subjects. In 81 healthy women aged 30-77 y, we compared the relative content of these 2 fatty acids in subcutaneous adipose tissue with relative intake (% of total fat) based on four 1-wk weighed diet records made 3-4 mo apart and on a food-frequency questionnaire reflecting average past year consumption. The mean (+/-SD) daily milk fat intake was 20.0 +/- 9.1 g and fat from ruminant meat was 3.0 +/- 1.5 g according to food records, representing 29.2 +/- 8.9% and 4.6 +/- 2.2% of total fat, respectively. The intake of 15:0 and 17:0, which are 1.05% and 0.61% of milk fat and 0.43% and 0.83% of ruminant meat fat, was 0.22 +/- 0.10 and 0.15 +/- 0.06 g, respectively. Content of 15:0 and 17:0 in adipose tissue was 0.35% and 0.24% and relative dietary intake was 0.33% and 0.22% according to the food records and 0.32% and 0.21%, respectively, according to the food-frequency questionnaire. Correlation coefficients between 15:0 content in adipose tissue and intake from dairy foods only, according to food records, were 0.63 (Pearson) and 0.59 (Spearman); corresponding values for 17:0 were 0.42 and 0.45, respectively. Content of 15:0 and 17:0 in subcutaneous adipose tissue might be a valid biological marker of long-term milk fat intake in free-living individuals in populations with high consumption of dairy products.
我们评估了反刍动物脂肪特有的两种外源脂肪酸（15:0和17:0）的脂肪组织含量是否反映了自由生活人群长期的平均乳制品脂肪摄入量。在81名年龄在30 - 77岁的健康女性中，我们将皮下脂肪组织中这两种脂肪酸的相对含量与基于相隔3 - 4个月的四份为期1周的称重饮食记录以及反映过去一年平均摄入量的食物频率问卷得出的相对摄入量（占总脂肪的百分比）进行了比较。根据食物记录，每日乳脂肪平均摄入量为20.0±9.1克，反刍动物肉类脂肪摄入量为3.0±1.5克，分别占总脂肪的29.2±8.9%和4.6±2.2%。15:0和17:0分别占乳脂肪的1.05%和0.61%，占反刍动物肉类脂肪的0.43%和0.83%，其摄入量分别为0.22±0.10克和0.15±0.06克。根据食物记录，脂肪组织中15:0和17:0的含量分别为0.35%和0.24%，相对饮食摄入量分别为0.33%和0.22%；根据食物频率问卷，相应含量分别为0.32%和0.21%。根据食物记录，脂肪组织中15:0含量与仅来自乳制品的摄入量之间的相关系数，Pearson法为0.63，Spearman法为0.59；17:0的相应值分别为0.42和0.45。在乳制品消费量大的人群中，皮下脂肪组织中15:0和17:0的含量可能是自由生活个体长期乳脂肪摄入量的有效生物学标志物。
