Asch S, Leake B, Knowles L, Gelberg L
West Los Angeles Veterans Administration Medical Center, CA 90073, USA.
Ann Emerg Med. 1998 Aug;32(2):144-7. doi: 10.1016/s0196-0644(98)70128-3.
Previous studies have had difficulty evaluating the optimal clinical site for screening homeless patients for active tuberculosis (TB). We hypothesized that homeless patients with TB would not frequently reside in shelters at the time of their diagnosis and would be more likely than other patients with TB to seek care in public hospitals, thus presenting an opportunity for screening radiography.
This registry-based survey included 743 consecutive patients with confirmed active TB in Los Angeles County. No therapeutic intervention was involved.
When compared with patients with TB who were not homeless, homeless patients with TB were more likely to be male (93% versus 63%, P<.001), black (44% versus 15%, P<.001), living in the inner city (55% versus 7%, P<.001), and born in the United States (67% versus 32%, P<.001). They were more infectious than other patients with TB as evidenced by a trend toward more cavitary radiographic lesions (24% versus 16%, P=.11) and significantly more positive sputum smears (56% versus 41%, P=.009). Less than a third lived in congregate facilities such as shelters at the time of their diagnosis. Instead, their disease was diagnosed more often at county hospitals (54% versus 23%, P<.001) than patients with TB who were not homeless.
Widespread screening for TB in shelters may miss most homeless patients with TB. Because most county-hospital homeless patients with TB initially present to emergency departments and many do not live in shelters, future cost-effectiveness studies should evaluate chest radiograph screening for all homeless ED patients.
以往的研究在评估为无家可归患者筛查活动性肺结核(TB)的最佳临床场所时遇到困难。我们推测,患有结核病的无家可归患者在确诊时不会经常居住在收容所,并且比其他结核病患者更有可能在公立医院寻求治疗,从而为进行筛查性放射照相提供了机会。
这项基于登记的调查纳入了洛杉矶县743例连续确诊的活动性结核病患者。未涉及任何治疗干预。
与非无家可归的结核病患者相比,无家可归的结核病患者更可能为男性(93%对63%,P<0.001)、黑人(44%对15%,P<0.001)、居住在市中心(55%对7%,P<0.001)且出生在美国(67%对32%,P<0.001)。他们比其他结核病患者更具传染性,表现为空洞性放射学病变有增多趋势(24%对16%,P=0.11),痰涂片阳性率显著更高(56%对41%,P=0.009)。不到三分之一的患者在确诊时居住在收容所等集体设施中。相反,与非无家可归的结核病患者相比,他们在县医院被诊断出疾病的比例更高(54%对23%,P<0.001)。
在收容所中广泛筛查结核病可能会遗漏大多数患有结核病的无家可归患者。由于大多数在县医院就诊的无家可归结核病患者最初是到急诊科就诊,而且许多人不住在收容所,未来的成本效益研究应评估对所有无家可归的急诊科患者进行胸部X光筛查。