Gomber S, Kumar S, Rusia U, Gupta P, Agarwal K N, Sharma S
Department of Paediatrics, University College of Medical Sciences, Delhi.
Indian J Med Res. 1998 Jun;107:269-73.
The present study was carried out to find out the prevalence and etiology of nutritional anaemia among preschool children from an urban slum. Randomly selected 300 children aged 3 months-3 yr were analysed over a period of one year for estimating prevalence of nutritional anaemia. Prevalence was also assessed by the rise in haemoglobin after 8 wk of haematinic supplementation in 159 of the 300 subjects. Ninety anaemic children were evaluated for the etiology of anaemia. Prevalence of anaemia, as judged by WHO recommended 'cut-off' value of haemoglobin < 11 g/dl, was 76 per cent while comparable value of 74.8 per cent was derived by response to haematinic supplementation. Pure iron deficiency anaemia (IDA) was detected in 41.4 per cent (37/90) of anaemic children. Vitamin B12 deficiency alone or in combination with iron was diagnosed in 14.4 and 22.2 per cent anaemic children respectively. Similarly folate deficiency, IDA with infection and anaemia of chronic diseases (ACD) was diagnosed in 2.2, 3.3 and 12.2 per cent cases respectively. Childhood anaemia continues to be a significant public health problem in preschoolers and iron deficiency is by far the commonest nutritional cause of anaemia. Vitamin B12 deficiency per se or in combination with iron is an important yet not commonly recognised cause of anaemias in preschool children in the community.
本研究旨在查明城市贫民窟学龄前儿童营养性贫血的患病率及病因。在一年时间里,对随机选取的300名年龄在3个月至3岁的儿童进行分析,以估算营养性贫血的患病率。还通过对300名受试者中的159名补充造血剂8周后血红蛋白的升高情况来评估患病率。对90名贫血儿童的贫血病因进行了评估。根据世界卫生组织推荐的血红蛋白<11 g/dl的“临界值”判断,贫血患病率为76%,而通过对造血剂补充的反应得出的可比数值为74.8%。在贫血儿童中,41.4%(37/90)检测出单纯缺铁性贫血(IDA)。分别有14.4%和22.2%的贫血儿童被诊断为单独维生素B12缺乏或合并缺铁。同样,分别有2.2%、3.3%和12.2%的病例被诊断为叶酸缺乏、IDA合并感染和慢性病贫血(ACD)。儿童贫血仍然是学龄前儿童中一个严重的公共卫生问题,缺铁是迄今为止最常见的营养性贫血原因。维生素B12缺乏本身或合并缺铁是社区学龄前儿童贫血的一个重要但尚未普遍认识到的原因。