Caulfield L E, Stoltzfus R J, Witter F R
Center for Human Nutrition, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21205, USA.
Am J Public Health. 1998 Aug;88(8):1168-74. doi: 10.2105/ajph.88.8.1168.
This study examined the relation between gestational weight gain and risk of delivering a small-for-gestational-age or large-for-gestational-age infant by race, along with the implications of gaining weight according to the Institute of Medicine guidelines.
Logistic regression methods were used to identify risk factors for small- and large-for-gestational-age births among 2617 Black and 1253 White women delivering at the Johns Hopkins Hospital between 1987 and 1989.
Rate of total weight gain was related to risk of small- and large-for-gestational-age births; the relationship differed according to maternal body mass index but not race. No differences in outcome by race were evident for women with low body mass indexes; among those with average or high indexes, however, Black women were at higher risk of small-for-gestational-age births and at lower risk of large-for-gestational-age births.
Having Black women gain at the upper end of the recommended range is unlikely to produce measurable reductions in small-for-gestational-age births. Some beneficial reductions in the risk of large-for-gestational-age births may occur if weight gain recommendations are lowered for average-weight and overweight White women.
本研究探讨了孕期体重增加与按种族划分的小于胎龄儿或大于胎龄儿分娩风险之间的关系,以及根据医学研究所指南增加体重的影响。
采用逻辑回归方法,对1987年至1989年在约翰霍普金斯医院分娩的2617名黑人妇女和1253名白人妇女中小于胎龄儿和大于胎龄儿出生的危险因素进行识别。
总体体重增加率与小于胎龄儿和大于胎龄儿出生风险相关;这种关系因孕妇体重指数而异,但与种族无关。体重指数低的女性在分娩结局上没有明显的种族差异;然而,在体重指数平均或较高的女性中,黑人女性小于胎龄儿出生的风险较高,大于胎龄儿出生的风险较低。
让黑人女性在推荐范围的上限增加体重不太可能使小于胎龄儿的出生率显著降低。如果降低平均体重和超重白人女性的体重增加建议,可能会使大于胎龄儿出生的风险有所降低。