Mamaeva T A, Tikhonova N T, Starov A I, Naumova M A, Vysotskiĭ V V
Vopr Virusol. 1998 May-Jun;43(3):127-9.
The liposomal technology for preparing the immunostimulating complex (ISCOM) helped obtain a complex measles preparation whose antigens are represented by the structural proteins of measles virus in the bilayer phosphate-lipid membrane. Immunization of mice with the resultant preparation induced antimeasles antibodies with the maximum titer of antihemagglutinins 1:640 and of antihemolysins 1:1280. The biological activity of antibodies was confirmed in the neutralization test.
用于制备免疫刺激复合物（ISCOM）的脂质体技术有助于获得一种复合麻疹制剂，其抗原由双层磷酸脂质膜中的麻疹病毒结构蛋白呈现。用所得制剂免疫小鼠可诱导产生抗麻疹抗体，抗血凝素的最大滴度为1:640，抗溶血素的最大滴度为1:1280。抗体的生物活性在中和试验中得到证实。
