人类和犬类球形细胞脑白质营养不良的形态学相似性。薄切片和冷冻断裂研究。

Am J Pathol. 1976 Oct;85(1):99-114.

Human and canine globoid leukodystrophy are shown to be indistinguishable morphologically. Both have characteristic deposits with polygonal cross-sectional profiles in addition to twisted ribbon-like structures. The specificity of the deposits is emphasized, and their laminated nature is corroborated by the freeze-fracture studies. Their apparently hollow profiles in cross section are thought to be produced by the tight arrangement of the bilayers that prevent penetration of the stain.

人类和犬类球状细胞脑白质营养不良在形态学上表现出无法区分的特征。两者除了有扭曲的带状结构外，都有具有多边形横截面轮廓的特征性沉积物。沉积物的特异性得到强调，其分层性质通过冷冻断裂研究得到证实。它们在横截面中明显的中空轮廓被认为是由双层紧密排列阻止染色剂渗透而产生的。