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亚浆膜线性密度：球样细胞和间充质细胞中的一种常见结构。

Sub-plasmalemmal linear density: a common structure in globoid cells and mesenchymal cells.

作者信息

Yajima K, Fletcher T F, Suzuki K

出版信息

Acta Neuropathol. 1977 Aug 31;39(3):195-200. doi: 10.1007/BF00691697.

DOI:10.1007/BF00691697
PMID:906802
Abstract

Sub-plasmalemmal linear densities of variable length (0.1 approximately 1.0 mu) were found to be a constant feature of globoid cells in human as well as in canine globoid cell leukodystrophy (GLD). Similar densities were also observed in experimental globoid cells and epithelioid cells in chronic granuloma but not in glial cells. The linear densities always appeared without any relation to basal laminae. These observations together with the other reports of similar structures in lymphoma, fibroma and sarcoidosis suggest that the sub-plasmalemmal density is a structure frequently observed in mesenchymal cells, and may be another supporting feature for possible mesenchymal origin of globoid cells.

摘要

在人类以及犬类球形细胞脑白质营养不良（GLD）中，发现可变长度（0.1至1.0微米左右）的亚细胞膜线性密度是球形细胞的一个恒定特征。在慢性肉芽肿的实验性球形细胞和上皮样细胞中也观察到了类似的密度，但在神经胶质细胞中未观察到。这些线性密度的出现总是与基底膜无关。这些观察结果以及淋巴瘤、纤维瘤和结节病中类似结构的其他报告表明，亚细胞膜密度是间充质细胞中经常观察到的一种结构，可能是球形细胞可能起源于间充质的另一个支持性特征。

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