Meijssen M A
Department of Gastroenterology and Internal Medicine II, University Hospital Rotterdam Dijkzigt, The Netherlands.
Mediators Inflamm. 1998;7(3):145-7. doi: 10.1080/09629359891054.
Cyclosporine is an effective drug in acute exacerbations of corticosteroid resistant ulcerative colitis, but its efficacy to maintain disease remission is not clear. Cyclosporine may not be as effective in Crohn's disease. However, being a rapidly acting immunosuppressant, cyclosporine may be a valuable therapeutic option in the short-term to treat corticosteroid resistant Crohn's disease and ulcerative colitis.
环孢素是治疗对皮质类固醇耐药的溃疡性结肠炎急性加重期的有效药物,但其维持疾病缓解的疗效尚不清楚。环孢素在克罗恩病中可能没有那么有效。然而,作为一种起效迅速的免疫抑制剂,环孢素在短期内治疗对皮质类固醇耐药的克罗恩病和溃疡性结肠炎时可能是一种有价值的治疗选择。