Gholizadeh Y, Varnerot A, Maslo C, Salauze B, Badaoui H, Vincent V, Buré-Rossier A
Laboratoire de Microbiologie, Hôpital Rothschild, Paris, France.
Eur J Clin Microbiol Infect Dis. 1998 Apr;17(4):278-81. doi: 10.1007/BF01699987.
Mycobacterium celatum is a recently described slow-growing species. It was identified on the basis of genomic sequencing that differentiates three types. The present report describes two cases of Mycobacterium celatum type 1 infection in patients with AIDS. Both patients had CD4+ lymphocyte counts of < 10/mm3, were receiving rifabutin prophylaxis, and had attended the same treatment units. The minimum inhibitory concentration of rifabutin for both strains was 8 mg/l, which may account for the failure of prophylaxis. As all type 1 strains have the same pulsed-field gel electrophoresis pattern, nosocomial transmission or acquisition from a common source could not be ruled out.
西氏分枝杆菌是一种最近才被描述的生长缓慢的菌种。它是根据基因组测序鉴定出来的，分为三种类型。本报告描述了两例艾滋病患者感染1型西氏分枝杆菌的病例。两名患者的CD4 +淋巴细胞计数均<10/mm3，正在接受利福布汀预防治疗，且曾在同一治疗单位就诊。两种菌株对利福布汀的最低抑菌浓度均为8 mg/l，这可能是预防治疗失败的原因。由于所有1型菌株具有相同的脉冲场凝胶电泳图谱，因此不能排除医院内传播或从共同来源获得感染的可能性。
