Salvatore C, Annunziata S, Gaffi M, Florio A, Lentini M, Pansadoro V
Divisioni di Urologia I e II Ospedale S. Camillo-Roma.
Arch Ital Urol Androl. 1998 Jun;70(3 Suppl):7-9.
Between January 1988 and December 1995 48 orthotopic detubularized and reconfigured ileal neobladder were carried out with two distinct surgical procedures in the same Hospital. 33 underwent lower urinary tract reconstruction using Studer's technique with an afferent ileal tubular isoperistaltic segment; in 15 patients the ileal substitution of the bladder was performed with Paduan ileal bladder (VIP). In any case an ileal low pressure reservoir was obtained with similar functional capacity (400 ml. at the urodynamic control), as using the same length of ileum (40 cm) for the reconstruction of the reservoir itself. In order to other functional aspects (e.g. diurnal and nocturnal continence) results were analogous if a correct rehabilitation program was observed. Significant post-voiding residual and late neobladder decompensation was prevented with adequate mictional training. Early and late complications (globally 19-24%) were evaluated: strictures of ureteroileal and ileo-urethral anastomoses were rare; an ileoureteral reflux was observed at a cystographic control in 50% of Studer group, but never clinically significant and only in 20% of VIPs. No clinically significant metabolic changes were found. Survival was satisfactory at a mean follow-up of 48 months.
1988年1月至1995年12月期间,同一家医院采用两种不同的手术方法对48例患者实施了原位去管化再构型回肠新膀胱术。33例患者采用施图德技术进行下尿路重建,使用传入性回肠管状等蠕动段;15例患者采用帕多瓦回肠膀胱术(VIP)进行膀胱回肠替代。无论采用哪种方法,使用相同长度(40 cm)的回肠重建储尿囊,均可获得功能容量相似(尿动力学检查时为400 ml)的低压回肠储尿囊。在其他功能方面(如日间和夜间控尿),如果遵循正确的康复方案,结果相似。通过充分的排尿训练可预防明显的排尿后残余尿量及晚期新膀胱失代偿。评估了早期和晚期并发症(总体发生率为19% - 24%):输尿管回肠和回肠尿道吻合口狭窄少见;在施图德组中,50%的患者在膀胱造影检查时观察到回输尿管反流,但临床上均无显著意义,在VIP组中仅为20%。未发现具有临床意义的代谢变化。平均随访48个月时,生存率令人满意。