Simecková A, Zamrazil V, Cerovská J
Institute of Endocrinology, Prague, Czech Republic.
Physiol Res. 1998;47(1):35-40.
We assessed the concentration of calcium, magnesium and creatinine in 2715 samples of the first morning urine. The investigation comprised the following age groups: children one, two, four, six, ten and thirteen years old, and groups of adults aged 18-35, 36-49, 50-65, 66-75, 76-85 and 86-93 years. The choice was made by random selection of participants of both sexes from diverse regions of the Czech Republic. We found the age to have a marked influence on the value of calcium, magnesium and creatinine, including urinary concentration ratios of calcium/creatinine and magnesium/creatinine. The urinary calcium concentration was low both in the early and advanced age groups, while it reached peak values in subjects 18-35 years old. The urinary magnesium concentration was also age-dependent, with a maximum in children aged 4 years, and a subsequent decline with advancing age. The value of the ratio urinary calcium/creatinine and urinary magnesium/creatinine was highest in the youngest age group (1-4 years).
我们对2715份首次晨尿样本中的钙、镁和肌酐浓度进行了评估。调查涵盖了以下年龄组:1岁、2岁、4岁、6岁、10岁和13岁的儿童,以及18 - 35岁、36 - 49岁、50 - 65岁、66 - 75岁、76 - 85岁和86 - 93岁的成年人组。通过从捷克共和国不同地区随机选择男女参与者来进行此项研究。我们发现年龄对钙、镁和肌酐的值,包括钙/肌酐和镁/肌酐的尿浓度比值有显著影响。早期和高龄年龄组的尿钙浓度较低,而在18 - 35岁的受试者中达到峰值。尿镁浓度也与年龄有关,4岁儿童中最高,随后随年龄增长而下降。尿钙/肌酐和尿镁/肌酐比值在最年轻的年龄组(1 - 4岁)中最高。