Calder J A, Lader J H
Appl Environ Microbiol. 1976 Jul;32(1):95-101. doi: 10.1128/aem.32.1.95-101.1976.
Dissolved aromatic hydrocarbons were found to decrease growth rate and maximum cell density of marine bacteria in batch cultures. The magnitude of the decrement was observed to be a function of concentration of the hydrocarbon and inherent toxicity. The inherent toxicity was observed to increase inversely with solubility such that naphthalene at 100 muM concentration demonstrated a toxic effect similar to benzopyrene at 0.02 muM. A partial oxidation product of naphthalene was found to be more effective in decreasing growth parameters than naphthalene at equivalent concentrations and to cause complete cessation of growth at the higher concentrations permitted by its polar structure.
在分批培养中发现,溶解的芳烃会降低海洋细菌的生长速率和最大细胞密度。观察到这种降低的幅度是烃类浓度和固有毒性的函数。观察到固有毒性与溶解度成反比增加,以至于浓度为100μM的萘表现出与浓度为0.02μM的苯并芘相似的毒性作用。发现在相同浓度下,萘的一种部分氧化产物在降低生长参数方面比萘更有效,并且在其极性结构允许的较高浓度下会导致生长完全停止。