Fleming A, Benn R T, Corbett M, Wood P H
Ann Rheum Dis. 1976 Aug;35(4):361-4. doi: 10.1136/ard.35.4.361.
Data from the first research clinic visit (Fleming and others, 1976) have been subjected to factor analysis to identify early patterns of joint involvement. Nine patterns emerged. Two patterns, if present early, were found to have prognostic significance. An eventually more severe disease was associated with a pattern of large joint involvement (shoulder, elbow, wrist, knee) and a pattern based on metatarsophalangeal joints I and III.
来自首次研究门诊就诊的数据（弗莱明等人，1976年）已进行因子分析，以确定关节受累的早期模式。出现了九种模式。发现其中两种模式若早期出现则具有预后意义。最终病情更严重与大关节受累模式（肩部、肘部、腕部、膝部）以及基于第一和第三跖趾关节的模式相关。
