Sicheritz-Pontén T, Kurland C G, Andersson S G
Department of Molecular Biology, Uppsala University, Sweden.
Biochim Biophys Acta. 1998 Jul 20;1365(3):545-51. doi: 10.1016/s0005-2728(98)00099-1.
We have cloned and sequenced the genes encoding cytochrome b (cob) and cytochrome c oxidase subunit I (cox1) from Rickettsia prowazekii, a member of the alpha-proteobacteria. The phylogenetic analysis supports the hypothesis that mitochondria are derived from the alpha-proteobacteria and more specifically from within the Rickettsiaceae. We have estimated that the common ancestor of mitochondria and Rickettsiaceae dates back to more than 1500 million years ago.
我们已经克隆并测序了来自普氏立克次体（一种α-变形菌）的编码细胞色素b（cob）和细胞色素c氧化酶亚基I（cox1）的基因。系统发育分析支持线粒体起源于α-变形菌，更具体地说，起源于立克次体科的假说。我们估计线粒体和立克次体科的共同祖先可追溯到15亿多年前。
