Simister N E
Rosenstiel Center for Basic Biomedical Sciences, W.M. Keck Institute for Cellular Visualization, Brandeis University, Waltham, MA 02254-9110, USA.
Vaccine. 1998 Aug-Sep;16(14-15):1451-5. doi: 10.1016/s0264-410x(98)00107-8.
Monomeric maternal antibodies are transmitted to the fetus, but most immune complexes are trapped in the placental stroma. The receptors responsible for trapping immune complexes appear to be Fc gamma RIa, Fc gamma RIIa, and Fc gamma RIIIa on stromal macrophages, and Fc gamma RII on fetal capillary endothelial cells.
单体母体抗体可传递给胎儿，但大多数免疫复合物被困在胎盘基质中。负责捕获免疫复合物的受体似乎是基质巨噬细胞上的FcγRIa、FcγRIIa和FcγRIIIa，以及胎儿毛细血管内皮细胞上的FcγRII。
