Benedik M J, Strych U
Department of Biochemical and Biophysical Sciences, University of Houston, TX 77204-5934, USA.
FEMS Microbiol Lett. 1998 Aug 1;165(1):1-13. doi: 10.1111/j.1574-6968.1998.tb13120.x.
Serratia marcescens produces an endonuclease with extraordinarily high specific activity that is released into the surrounding medium. This enzyme has been the focus of studies on gene regulation, protein secretion, endonuclease action, and protein structure; it has also been found to have many applications in biotechnology. Here we briefly review these different facets of research regarding the Serratia nuclease and summarize the current state of knowledge about this enzyme.
粘质沙雷氏菌产生一种具有极高比活性的核酸内切酶,该酶会释放到周围培养基中。这种酶一直是基因调控、蛋白质分泌、核酸内切酶作用和蛋白质结构研究的重点;它还被发现在生物技术中有许多应用。在此,我们简要回顾关于粘质沙雷氏菌核酸酶研究的这些不同方面,并总结有关这种酶的当前知识状态。