炎性平滑肌肉瘤可能具有特定的近单倍体染色体变化特征。
Inflammatory leiomyosarcoma may be characterized by specific near-haploid chromosome changes.
作者信息
Dal Cin P, Sciot R, Fletcher C D, Samson I, De Vos R, Mandahl N, Willén H, Larsson O, Van den Berghe H
机构信息
Centre for Human Genetics, University of Leuven, Belgium.
出版信息
J Pathol. 1998 May;185(1):112-5. doi: 10.1002/(SICI)1096-9896(199805)185:1<112::AID-PATH54>3.0.CO;2-U.
Abstract
Identical near-haploid karyotypes with 28, X, +5, +18, +20, +21, +22 were found in two cases of inflammatory leiomyosarcoma, one of which had been reported previously as malignant fibrous histiocytoma. This abnormality may identify these tumours as a separate entity within this group of sarcomas.
摘要
在两例炎症性平滑肌肉瘤中发现了相同的近单倍体核型，即28,X,+5,+18,+20,+21,+22，其中一例先前曾被报告为恶性纤维组织细胞瘤。这种异常可能将这些肿瘤确定为该组肉瘤中的一个独立实体。
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