Taxel P
Department of Geriatrics, University of Connecticut, Farmington, USA.
Geriatrics. 1998 Aug;53(8):22-3, 27-8, 33 passim.
Osteoporosis is a silent disease that often remains asymptomatic and undetected until bone fracture occurs. Because of the high morbidity associated with fracture, prevention is a clinical priority. In order to identify those who would benefit from therapeutic intervention, bone density measurement is indicated in patients with risk factors for osteoporosis. Therapies include hormone replacement, calcitonin, bisphosphonates, and selective estrogen receptor modulators, as well as exercise and supplements of calcium and vitamin D. The goal of all treatments is to decrease the risk of fracture by minimizing bone loss and increasing bone mass.
骨质疏松症是一种隐匿性疾病，通常没有症状，在发生骨折之前往往未被发现。由于骨折相关的高发病率，预防是临床的首要任务。为了确定哪些人将从治疗干预中获益，对于有骨质疏松症危险因素的患者，需要进行骨密度测量。治疗方法包括激素替代疗法、降钙素、双膦酸盐、选择性雌激素受体调节剂，以及运动和补充钙和维生素D。所有治疗的目标都是通过减少骨质流失和增加骨量来降低骨折风险。
