Takeuchi E, Yanagawa H, Nishikubo N, Ogushi F, Sone S
Third Department of Internal Medicine, University of Tokushima School of Medicine, Japan.
Anticancer Res. 1998 Jul-Aug;18(4B):2815-7.
Although involvement of the heart is not a rare manifestation of malignant lymphoma, most cases are diagnosed by postmortem examination. In the present article, we describe a man with metastatic cardiac lymphoma with complete A-V block successfully treated by resection of the heart tumor and sequential combination chemotherapy with cyclophosphamide, doxorubicin, vincristine and predonisolone and radiation therapy. Combination modality resulted in complete disappearance of signs of heart failure and A-V block. Our experience indicated that early diagnosis and combination modality can obtain long survival in case of metastatic cardiac lymphoma.
尽管心脏受累并非恶性淋巴瘤的罕见表现，但大多数病例是在尸检时才得以诊断。在本文中，我们描述了一名患有转移性心脏淋巴瘤并伴有完全性房室传导阻滞的男性患者，通过切除心脏肿瘤以及先后联合使用环磷酰胺、阿霉素、长春新碱和强的松龙进行化疗并结合放疗，成功治愈。联合治疗方式使心力衰竭和房室传导阻滞的症状完全消失。我们的经验表明，对于转移性心脏淋巴瘤，早期诊断和联合治疗方式可使患者获得较长生存期。
