Shrestha S P, Hennig A, Parija S C
Department of Ophthalmology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
Am J Trop Med Hyg. 1998 Aug;59(2):231-4. doi: 10.4269/ajtmh.1998.59.231.
This study describes the clinical features, diagnosis, and treatment of rhinosporidiosis of the eye and its adnexa in a series of 76 cases in Nepal and six originating in India. The disease caused by the fungus Rhinosporidium seeberi was seen most frequently in young children between eight and 10 years of age. Males were infected more than females (2.5:1). The conjunctiva was the most common site of infection in 76 (92.68%) of the cases. The lacrimal sac was affected only in six (7.32%) cases. Simple total excision of the conjunctival polyps gave highly satisfactory results in cases of conjunctival sac infections. Except for one patient, there were no recurrences in the 76 cases. Meticulous excision of polyps provided a satisfactory result in the treatment of six cases with lacrimal sac infection. Recurrence was noted in one of these six cases followed up to two and a half years after surgery. The conditions diagnosed clinically were confirmed by histopathology. This review of 82 cases is the first such report of rhinosporidiosis from Nepal.
本研究描述了尼泊尔76例以及印度6例眼及其附属器鼻孢子虫病的临床特征、诊断及治疗情况。由西伯鼻孢子菌引起的该病在8至10岁的儿童中最为常见。男性感染多于女性（2.5:1）。76例（92.68%）中最常见的感染部位是结膜。仅6例（7.32%）泪囊受累。对于结膜囊感染病例，单纯彻底切除结膜息肉效果非常令人满意。76例中除1例患者外均无复发。精心切除息肉对6例泪囊感染的治疗效果令人满意。这6例中有1例在术后随访至两年半时出现复发。临床诊断的病情经组织病理学证实。这篇对82例病例的综述是来自尼泊尔的关于鼻孢子虫病的首例此类报告。
