P300波幅与苏达山克里亚瑜伽（SKY）的抗抑郁反应
P300 amplitude and antidepressant response to Sudarshan Kriya Yoga (SKY).
作者信息
Naga Venkatesha Murthy P J, Janakiramaiah N, Gangadhar B N, Subbakrishna D K
机构信息
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
出版信息
J Affect Disord. 1998 Jul;50(1):45-8. doi: 10.1016/s0165-0327(98)00029-9.
BACKGROUND
There is evidence that Sudarshan Kriya Yoga (SKY) has significant antidepressant effects.
OBJECTIVE
The present study examined whether pretreatment P300 ERP amplitude predicts antidepressant response to SKY.
METHODS
Consenting, drug-free depressed patients (n = 30; dysthymics, 15, melancholics, 15) who received SKY as the sole treatment were assessed clinically at pretreatment, 1 month and 3 months. Auditory P300 was recorded before treatment.
RESULTS
Twenty-two patients responded favourably to SKY. The pretreatment P300 amplitude neither distinguished responders and non-responders nor was associated with differential rates of response.
DISCUSSION
It is concluded that SKY therapy is uniformly effective regardless of the pretreatment P300 amplitude.
背景
有证据表明，苏达山克里亚瑜伽（SKY）具有显著的抗抑郁作用。
目的
本研究旨在探讨治疗前P300事件相关电位（ERP）波幅是否能预测SKY的抗抑郁反应。
方法
选取30例同意参与且未服用药物的抑郁症患者（恶劣心境障碍患者15例，重度抑郁障碍患者15例），将SKY作为唯一治疗方法，并在治疗前、治疗1个月和3个月时进行临床评估。在治疗前记录听觉P300。
结果
22例患者对SKY治疗反应良好。治疗前P300波幅既不能区分反应者和无反应者，也与不同的反应率无关。
讨论
得出的结论是，无论治疗前P300波幅如何，SKY疗法均具有一致的疗效。
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