Gjerde H, Fongen U, Gundersen H, Christophersen A S
National Institute of Forensic Toxicology, Oslo, Norway.
Forensic Sci Int. 1991 Oct;51(1):105-10. doi: 10.1016/0379-0738(91)90210-a.
Codeine, ethylmorphine and morphine are the most commonly detected opiates in forensic blood samples in Norway. A method for the simultaneous quantification of these opiates utilizing solid phase extraction and gas chromatography-mass spectrometry has been evaluated. The detection limits were 0.026 mumol/l for codeine, 0.025 mumol/l for ethylmorphine and 0.032 mumol/l for morphine (corresponding to 7.8, 7.8 and 9.1 micrograms/l, respectively). The analytical variations at concentrations of 1.0 mumol/l codeine, 1.0 mumol/l ethylmorphine and 0.5 mumol/l morphine were less than 5%.
