Use of the Malthus-AT system to assess the efficacy of permeabilizing agents on the activity of antibacterial agents against Pseudomonas aeruginosa.
作者信息
Ayres H M, Payne D N, Furr J R, Russell A D
机构信息
Welsh School of Pharmacy, University of Wales Cardiff, UK.
出版信息
Lett Appl Microbiol. 1998 Jun;26(6):422-6. doi: 10.1046/j.1472-765x.1998.00364.x.
Abstract
The Malthus-AT system provided a satisfactory method for examining the effects of permeabilizing agents on the activity of sub-inhibitory concentrations of antibacterial agents against Pseudomonas aeruginosa G48. Under this system, disodium edetate potentiated the activity of chlorhexidine diacetate (CHA), cetylpyridinium chloride, para-chlorometaxylenol and triclosan. Nitrilotriacetic acid enhanced the activity of some of the antibacterials tested, whereas sodium polyphosphate markedly reduced the efficacy of CHA.
摘要
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