Jithendran K P, Somvanshi R
Indian Veterinary Research Institute, Regional Station, Palampur, India.
Indian J Exp Biol. 1998 May;36(5):523-5.
Cysticercus fasciolaris, the larval form of Taenia taeniaformis is commonly encountered in rodents most often in mice and rats through contaminated feed and bedding materials. The infection is asymptomatic and is considered harmless, but its presence in the laboratory mice/rats could lead to misinterpretation of results for biological experiments. The course of infection and pathogenesis of induced C. fasciolaris was studied in Swiss albino mice. The number of established cysts were not significantly different during the course of infection. The mean diameter of the cysts and the metacestode were significantly different during the course of infection reaching a maximum size of 8.1 +/- 2.2 mm and 80.4 +/- 20.2 mm, respectively on 45 DPI. Histopathologically, on 15 DPI, the duodenum of the affected mice revealed cross sections of early larval stage of C. fasciolaris. On 30 and 45 DPI, the liver showed tract of migration of C. fasciolaris larvae with a thick zone of inflammatory reaction and encapsulation against mature larvae in liver. The routine spontaneous Cystucercus infection is clinically asymptomatic in these animals and is considered harmless. The present experimental infection also followed the same course resulting only in asymptomatic colonisation of the parasites.
豆状囊尾蚴是豆状带绦虫的幼虫形式，通常通过受污染的饲料和垫料材料在啮齿动物（最常见于小鼠和大鼠）中出现。这种感染没有症状，被认为是无害的，但它在实验室小鼠/大鼠中的存在可能会导致生物学实验结果的错误解读。在瑞士白化小鼠中研究了诱导感染的豆状囊尾蚴的感染过程和发病机制。在感染过程中，已形成囊肿的数量没有显著差异。在感染过程中，囊肿和囊尾蚴的平均直径有显著差异，在感染后45天分别达到最大尺寸8.1±2.2毫米和80.4±20.2毫米。组织病理学上，在感染后15天，受影响小鼠的十二指肠显示出豆状囊尾蚴幼虫早期阶段的横截面。在感染后30天和45天，肝脏显示出豆状囊尾蚴幼虫的迁移轨迹，伴有厚厚的炎症反应带以及对肝脏中成熟幼虫的包囊。在这些动物中，常规的自发性囊尾蚴感染在临床上没有症状，被认为是无害的。目前的实验性感染也遵循相同的过程，仅导致寄生虫的无症状定植。
