Tilak T B, Nagarajan V, Tulpule P G
Experientia. 1976 Sep 15;32(9):1179-80. doi: 10.1007/BF01927613.
Male rats kept at a temperature of 4 degrees-5 degrees C were refractory to a lethal dose of aflatoxin compared to animals at 20 degrees-21 degrees C which exhibited a high mortality and marked liver damage. It is suggested that this decreased susceptibility is mediated through a stimulated microsomal drug-metabolizing system in cold environment.
