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钬:钇铝石榴石激光治疗胆石症

Treatment of biliary calculi using holmium: yttrium aluminum garnet laser.

作者信息

Das A K, Chiura A, Conlin M J, Eschelman D, Bagley D H

机构信息

Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

出版信息

Gastrointest Endosc. 1998 Aug;48(2):207-9. doi: 10.1016/s0016-5107(98)70167-1.

Abstract

BACKGROUND

The holmium: yttrium aluminum garnet laser (Ho: YAG) has been shown to be effective and safe for the treatment of urinary calculi. Its effectiveness for the treatment of biliary calculi was investigated.

METHODS

Endoscopic Ho: YAG lithotripsy of biliary stones was performed 7 times in 4 patients. Two patients had biliary duct calculi, and the other two patients had gall bladder calculi. All patients had multiple calculi that ranged in size from 4 mm to 5 cm. All procedures were performed percutaneously under intravenous sedation and local anesthesia. Rigid and flexible endoscopes were used to access the biliary calculi. Postoperative cholangiograms were performed on all patients.

RESULTS

All calculi were successfully fragmented with the Ho: YAG laser. The most common settings on the laser were 1.0 J and 10 Hz. Average total laser energy used was 12.24 kJ. Two patients required multiple procedures for the resolution of the biliary calculi. No vascular or biliary injuries were encountered. Three patients were free of biliary calculi on their postoperative cholangiogram. One patient with multiple gallbladder stones refused further treatment after two percutaneous procedures.

CONCLUSION

The holmium: yttrium aluminum garnet laser can be used safely and effectively in the endoscopic treatment of biliary calculi. This treatment maybe a suitable option in patients who are not candidates for more invasive procedures.

摘要

背景

钬:钇铝石榴石激光(Ho:YAG)已被证明在治疗尿路结石方面有效且安全。对其治疗胆结石的有效性进行了研究。

方法

对4例患者进行了7次内镜下Ho:YAG激光碎石术治疗胆结石。2例患者有胆管结石,另外2例患者有胆囊结石。所有患者均有多颗结石,大小从4毫米到5厘米不等。所有手术均在静脉镇静和局部麻醉下经皮进行。使用硬性和软性内镜进入胆结石部位。所有患者均进行了术后胆管造影。

结果

所有结石均被Ho:YAG激光成功击碎。激光最常用的参数设置为1.0焦耳和10赫兹。平均总激光能量使用为12.24千焦。2例患者需要多次手术以清除胆结石。未发生血管或胆管损伤。3例患者术后胆管造影显示无胆结石。1例有多颗胆囊结石的患者在两次经皮手术后拒绝进一步治疗。

结论

钬:钇铝石榴石激光可安全有效地用于内镜下治疗胆结石。对于不适合进行更具侵入性手术的患者,这种治疗可能是一种合适的选择。

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