Kronner K M, Casale A J, Cain M P, Zerin M J, Keating M A, Rink R C
Department of Pediatric Urology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, USA.
J Urol. 1998 Sep;160(3 Pt 2):1096-8; discussion 1103. doi: 10.1097/00005392-199809020-00035.
Bladder augmentation is now a commonly accepted treatment in children with neuropathic bladder and other bladder anomalies. Bladder calculi have been reported in a third to a half of pediatric patients after bladder augmentation. We identify the incidence of bladder calculi and risk factors for stone formation in a large series of pediatric patients after bladder augmentation.
We reviewed the records of 286 patients who underwent bladder augmentation between 1978 and 1994, assessed the incidence of and risk factors for bladder calculi, and reviewed treatment methods.
Bladder calculi developed in 29 of the 286 patients (10%) who underwent bladder augmentation. The type of bowel used for augmentation did not affect the rate of stone formation except stomach, which did not lead to stone formation in any case. Stones formed more commonly after bladder outlet resistance procedures and in patients with catheterizable abdominal wall stomas. Patients underwent open cystolithotomy or cystolitholapaxy with an overall 44% recurrence rate and no statistically significant difference between treatment methods.
Bladder calculi are a known complication of bladder augmentation. An increased risk of stone formation is associated with bladder outlet resistance procedures and catheterizable abdominal wall stomas. Daily irrigations to clear mucus and crystals as well as complete emptying of the augmented bladder may have important roles in decreasing stone formation.
膀胱扩大术目前是治疗神经源性膀胱及其他膀胱异常患儿的常用方法。据报道,三分之一至半数接受膀胱扩大术的儿科患者会出现膀胱结石。我们在大量接受膀胱扩大术的儿科患者中确定膀胱结石的发生率及结石形成的危险因素。
我们回顾了1978年至1994年间接受膀胱扩大术的286例患者的记录,评估膀胱结石的发生率及危险因素,并回顾治疗方法。
286例接受膀胱扩大术的患者中有29例(10%)发生膀胱结石。用于扩大术的肠段类型除胃(任何情况下均未导致结石形成)外,不影响结石形成率。膀胱出口阻力手术及有可导尿腹壁造口的患者结石形成更为常见。患者接受开放性膀胱切开取石术或膀胱碎石术,总体复发率为44%,治疗方法之间无统计学显著差异。
膀胱结石是膀胱扩大术已知的并发症。结石形成风险增加与膀胱出口阻力手术及可导尿腹壁造口有关。每日冲洗以清除黏液和晶体以及完全排空扩大的膀胱在减少结石形成方面可能起重要作用。