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[与6号染色体相关的、控制果蝇成虫保幼激素降解系统对应激反应的基因]

[Genes, controlling the response of the juvenile hormone degradation system to stress in the Drosophila virilis imago, linked to chromosome 6].

作者信息

Khlebadarova T M, Grenbék L G, Gruntenko N E, Sukhanova M Zh, Vasenkova I A, Shumnaia L V, Raushenbakh I Iu

机构信息

Institute of Cytology and Genetics, Russian Academy of Sciences Novosibirsk, Russia.

出版信息

Genetika. 1998 May;34(5):625-8.

PMID:9719911
Abstract

Chromosome localization of the gene controlling the stress response of DFP-sensitive juvenile hormone (JH) esterase in females of Drosophila virilis was conducted. Line 160 of D. virilis carrying recessive markers on all chromosomes was used as a tester. Mature females of line 160 were shown to exhibit a high level of JH hydrolysis; these flies responded to stress by a sharp decrease in JH hydrolysis. Flies from line 147 lacked this response. Thus, mature females of lines 160 and 147 had different levels of JH hydrolysis under heat stress. F2 hybrids that inherited one chromosome pair from flies of line 147 and the remaining chromosomes, from flies of line 147 were analyzed. This analysis showed that the D. virilis gene controlling the stress response of the JH degradation system is linked with chromosome 6.

摘要

对控制果蝇雌性中对二异丙基氟磷酸敏感的保幼激素(JH)酯酶应激反应的基因进行了染色体定位。使用在所有染色体上都携带隐性标记的果蝇160品系作为测试品系。已证明果蝇160品系的成熟雌性表现出高水平的JH水解;这些果蝇通过JH水解的急剧下降对应激作出反应。来自147品系的果蝇缺乏这种反应。因此,160品系和147品系的成熟雌性在热应激下具有不同水平的JH水解。分析了从147品系果蝇继承一对染色体,其余染色体从147品系果蝇继承的F2杂种。该分析表明,控制JH降解系统应激反应的果蝇基因与6号染色体连锁。

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