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[颅内动脉瘤的遗传因素(对同卵双胞胎的研究)]

[Heredity in intracranial aneurysms (a study of identical twins)].

作者信息

Sakovich V P, Lebedeva E R, Nalesnik M V

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1998 Apr-Jun(2):33-5.

PMID:9720167
Abstract

The study of identical twins revealed an important role of hereditary factors in the development of cerebral aneurysms. The "weakness" of connective tissue, caused by some genetic (or polygenic) defects, concurrent with several acquired conditions (essential hypertension, connective tissue disorders) leads to the development and rupture of cerebral aneurysms.

摘要

对同卵双胞胎的研究揭示了遗传因素在脑动脉瘤发展中的重要作用。由某些基因(或多基因)缺陷导致的结缔组织“薄弱”,与几种后天性疾病(原发性高血压、结缔组织疾病)同时存在,会导致脑动脉瘤的形成和破裂。

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