Pope J C, Keating M A, Casale A J, Rink R C
Division of Pediatric Urology, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana, USA.
J Urol. 1998 Sep;160(3 Pt 1):854-7. doi: 10.1016/S0022-5347(01)62820-9.
Bowel used for bladder reconstruction regardless of detubularization occasionally retains its contractile properties. Of 323 patients who underwent primary enterocystoplasty we identified 19 who continue to have high pressure bladder contractions and required augmentation of the previously augmented bladder.
Reason for repeat augmentation, upper tract changes, original and secondary bowel segments used, and urodynamic findings were evaluated in all patients. Current status and followup also were noted.
After initial augmentation 8 patients had persistent incontinence, 5 bladder perforation, 3 isolated upper tract changes, 2 incontinence and bladder perforation, and 1 incontinence plus intractable pain. Preoperative urodynamics revealed detrusor pressures from 30 to 100 cm. water. All patients had adequate bladder outlet resistance. The original bowel segments used were sigmoid in 12 cases, stomach in 4, ileum in 2 and cecum in 1. Bowel segments for re-augmentation were ileum in 16 cases and sigmoid in 3. Of the 11 patients with incontinence 10 are now dry. All cases of upper tract changes resolved. Mean followup since re-augmentation is 52 months.
If the outcome of bladder augmentation is less than optimal, it is important to reevaluate the bladder dynamics. In rare instances these patients may continue to have high pressure contractions with a functionally small bladder capacity. In such situations reaugmentation with an additional bowel segment is an excellent alternative to a difficult clinical problem and provides good results in the vast majority of cases. This treatment may not totally alleviate the contractions but it does decrease them and increase the volumes at which the contractions occur, making them no longer clinically or functionally significant.
用于膀胱重建的肠管,无论是否去管化,偶尔都会保留其收缩特性。在323例行初次肠膀胱扩大术的患者中,我们确定有19例持续存在膀胱高压收缩,需要对先前已扩大的膀胱进行再次扩大。
评估所有患者再次扩大的原因、上尿路变化、最初及二次使用的肠段以及尿动力学检查结果。记录当前状况及随访情况。
初次扩大术后,8例患者持续存在尿失禁,5例发生膀胱穿孔,3例出现孤立的上尿路变化,2例既有尿失禁又有膀胱穿孔,1例有尿失禁加顽固性疼痛。术前尿动力学检查显示逼尿肌压力为30至100厘米水柱。所有患者膀胱出口阻力均正常。最初使用的肠段中,12例为乙状结肠,4例为胃,2例为回肠,1例为盲肠。再次扩大所用的肠段中,16例为回肠,3例为乙状结肠。11例尿失禁患者中,10例现已无尿失禁。所有上尿路变化的病例均已缓解。再次扩大术后的平均随访时间为52个月。
如果膀胱扩大术的效果不理想,重新评估膀胱动力学很重要。在极少数情况下,这些患者可能仍会有高压收缩,且膀胱功能容量较小。在这种情况下,用额外的肠段再次扩大是解决这一棘手临床问题的极佳选择,并且在绝大多数病例中能取得良好效果。这种治疗可能无法完全消除收缩,但确实能减轻收缩程度,并增加发生收缩时的容量,使其在临床或功能上不再具有重要意义。