Patrizi A, Neri I, Fiorentini C, Marzaduri S
Department of Clinical and Experimental Medicine, University of Bologna, Italy.
Pediatr Dermatol. 1998 Jul-Aug;15(4):304-6. doi: 10.1046/j.1525-1470.1998.1998015304.x.
Nevus comedonicus (NC) is an uncommon developmental defect of the pilosebaceous apparatus. The individual lesions are large comedones often arranged in groups or in a linear pattern. Nevus comedonicus syndrome (NCS) is a well-defined disorder within the large group of epidermal nevus syndromes. In patients suffering from NCS, the nevus is associated with noncutaneous abnormalities including skeletal defects, cerebral anomalies, and cataracts. We report a 9-year-old boy with open comedones in a linear pattern localized to the right cheek, clinodactyly and polydactyly of the first right finger, bilateral syndactyly of the second and third toes, and some depigmented hairs since birth.
粉刺痣（NC）是一种罕见的毛囊皮脂腺发育缺陷。单个损害为大的粉刺，常成群或呈线状排列。粉刺痣综合征（NCS）是一大类表皮痣综合征中一种明确的疾病。患有NCS的患者，其痣与包括骨骼缺陷、脑异常和白内障在内的非皮肤异常有关。我们报告一名9岁男孩，自出生以来，其右脸颊有呈线状排列的开放性粉刺，右手拇指斜指畸形并多指畸形，双侧第二和第三趾并指畸形，还有一些色素脱失的毛发。
