Lindow S W, Hendricks M S, Thompson J W, van der Spuy Z M
Department of Obstetrics and Gynaecology, Groot Schuur Hospital, Cape Town, South Africa.
Eur J Obstet Gynecol Reprod Biol. 1998 Aug;79(2):127-9. doi: 10.1016/s0301-2115(98)00073-6.
The presence of a supportive companion to women in labour has been found to reduce the duration of labour and the incidence of oxytocin augmentation. The mechanism which produces this improvement is unknown but work in animals suggests that environmental disturbance produces changes in endogenous oxytocin secretion. This study was carried out to assess maternal oxytocin secretion in relation to the presence of a supportive companion in labour.
A randomised controlled trial involving allocation of unsupported women in the first stage of labour to a period of 1 h with a supportive companion or 1 h without. Sixteen women with uncomplicated singleton pregnancies who were in the active phase of the first stage of labour were studied. Maternal oxytocin levels were assayed by radioimmunoassay for 16 min (eight specimens) before and after the support or control period.
There are no differences between maternal oxytocin levels in the two groups of patients. There was no difference in either of the two groups between the oxytocin levels pre and post the support/control period.
One hour of birth support in the first stage of labour did not improve maternal oxytocin levels when compared to a control group.
研究发现，分娩时若有支持陪伴者在场，可缩短产程并降低缩宫素增加的发生率。产生这种改善效果的机制尚不清楚，但动物实验表明，环境干扰会导致内源性缩宫素分泌发生变化。本研究旨在评估分娩时支持陪伴者的存在与产妇缩宫素分泌之间的关系。
一项随机对照试验，将第一产程中无支持陪伴的产妇随机分配，一组接受支持陪伴者陪伴1小时，另一组不接受陪伴1小时。对16例处于第一产程活跃期、单胎妊娠且无并发症的产妇进行了研究。在支持或对照期前后，通过放射免疫分析法对产妇缩宫素水平进行16分钟（8个样本）的检测。
两组患者的产妇缩宫素水平无差异。支持/对照期前后，两组的缩宫素水平均无差异。
与对照组相比，第一产程中1小时的分娩支持并未提高产妇缩宫素水平。
