Kettunen J, Mäkelä E A, Miettinen H, Nevalainen T, Heikkilä M, Pohjonen T, Törmälä P, Rokkanen P
Department of Surgery, Kuopio University Hospital, Finland.
Biomaterials. 1998 Jul;19(14):1219-28. doi: 10.1016/s0142-9612(98)00027-1.
A novel composite material with ultra-high flexural strength and cortical-bone-matched elastic modulus made of liquid crystalline polymer reinforced with carbon fibres (LCP/CF) is described. Cylindrical rods of 3.2 mm diameter and 50 mm length were fabricated by a preimpregnation/pultrusion method. The initial mechanical properties of the LCP/CF rods were as follows: flexural strength 448 MPa, flexural modulus 43 GPa, shear strength 164 MPa, and interlaminar shear strength 15.3 MPa. In the in vitro study the LCP/CF rods were immersed in phosphate-buffered saline of 37 degrees C for 12, 24, and 52 weeks. In the in vivo study the LCP/CF rods were implanted into the medullary cavity of both femora and subcutaneous tissue of the New Zealand White rabbits for 12, 24, and 52 weeks. The flexural strength of the LCP/CF rods at 52 weeks was 463 MPa in saline, 467 MPa in the subcutaneous tissue and 466 MPa in the medullary cavity of the femur. The flexural modulus was 44.6, 48.9 and 46.2 GPa, respectively. The corresponding shear strength values were 160, 178 and 181 MPa. We conclude that the LCP/CF is a promising material for high-load applications and the LCP/CF rods retain their initial mechanical properties in one-year follow-up in vivo and in vitro.
本文描述了一种由碳纤维增强液晶聚合物（LCP/CF）制成的具有超高抗弯强度和与皮质骨匹配弹性模量的新型复合材料。通过预浸/拉挤成型法制备了直径3.2毫米、长度50毫米的圆柱形棒材。LCP/CF棒材的初始力学性能如下：抗弯强度448兆帕、抗弯模量43吉帕、剪切强度164兆帕和层间剪切强度15.3兆帕。在体外研究中，将LCP/CF棒材浸入37摄氏度的磷酸盐缓冲盐水中12周、24周和52周。在体内研究中，将LCP/CF棒材植入新西兰白兔的双侧股骨骨髓腔和皮下组织中12周、24周和52周。52周时，LCP/CF棒材在盐水中的抗弯强度为463兆帕，在皮下组织中为467兆帕，在股骨骨髓腔中为466兆帕。抗弯模量分别为44.6吉帕、48.9吉帕和46.2吉帕。相应的剪切强度值分别为160兆帕、178兆帕和181兆帕。我们得出结论，LCP/CF是一种适用于高负荷应用的有前景的材料，并且LCP/CF棒材在体内和体外一年的随访中保持其初始力学性能。
