Montgomery M, Witt H, Kuylenstierna R, Frenckner B
Department of Pediatric Surgery, St. Göran's/Karolinska Hospital, Karolinska Institute, Stockholm, Sweden.
J Pediatr Surg. 1998 Aug;33(8):1219-23. doi: 10.1016/s0022-3468(98)90154-3.
Patients with repaired esophageal atresia often show persistent motility disorders of the esophagus.
In this study, the authors used a newly developed method, videomanometry, to study intraluminal pressures and function of the pharynx and upper esophagus in such a group of patients and compared the results with those in healthy age-matched controls.
A significant difference was found between timing of the pharynx contraction and upper esophageal sphincter (UES) relaxation, indicating a dyscoordination of swallowing in the patient group. Transit time of bolus from the pharynx to the esophagus was also shorter for the patient group. Such dyscoordination may be a risk factor that can cause aspiration and respiratory symptoms.
UES resting pressure and residual pressure on swallowing, did not differ between the two groups.
食管闭锁修复术后的患者常表现出持续性食管动力障碍。
在本研究中,作者使用一种新开发的方法——视频测压法,来研究该组患者的咽和食管上段的腔内压力及功能,并将结果与年龄匹配的健康对照组进行比较。
发现患者组咽收缩和食管上括约肌(UES)松弛的时间存在显著差异,表明患者组吞咽失调。患者组食团从咽到食管的通过时间也较短。这种失调可能是导致误吸和呼吸道症状的危险因素。
两组之间UES静息压力和吞咽时的残余压力无差异。